Flax has also been used to treat osteoporosis. Flax has been used in alternative medicine as a possibly effective aid in treating type 2 diabetes, high cholesterol, and some autoimmune diseases such as systemic lupus erythematosus (SLE). Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Adolescent dietary phytoestrogen intake and breast cancer risk (Canada). Dont take flaxseed oil or flax seeds in pregnancy or while breastfeeding. Albuterol Inhalation (Ventolin) Amoxicillin (Amoxil) Azithromycin (Zithromax) CoQ10 (Coenzyme Q-10) Ibuprofen (Advil) Levothyroxine (Synthroid) Lexapro (Escitalopram) Lipitor (Atorvastatin) . Mohammadi-Sartang M, Mazloom Z, Raeisi-Dehkordi H, Barati-Bodaji R, Bellisimo N, Totosy de Zepetnek JO. The effect of flaxseed supplementation on early risk markers for mammary carcinogenesis. Information from this source is evidence-based and objective, and without commercial influence. Chan School of Public Health, 17 Reasons Why You Probably Need More Omega-3s in Your Diet, National Center for Complementary and Integrative Health. View abstract. Am J Clin Nutr 2004;79:318-25.. View abstract. Furthermore, some blood thinners, NSAID pain killers, hormone treatments, and certain medications for blood pressure, cholesterol, and diabetes may interact with flaxseed oil and flaxseed. View abstract. View abstract. The phase IV clinical study analyzes what interactions people who take Flaxseed and Anastrozole have. Dodin S, Lemay A, Jacques H, et al. The authors of the article in the Journal of Food Science and Technology call flaxseed oil a functional food because of its potential health benefits. J Nutr. Flaxseed and flaxseed oil. Effect of a homemade salivary substitute prepared using chamomile (Matricaria chamomilla L.) flower and flax (Linum usitatissimum L.) seed to relieve primary burning mouth syndrome: a preliminary report. View abstract. Is flaxseed good for everyone? Kuijsten A, Arts IC, Hollman PC, et al. Black Seed Oil and Diabetes: What's Known, What's Not, Harvard T.H. High dose flaxseed oil supplementation may affect fasting blood serum glucose management in human type 2 diabetics. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use. PAF is an active compound in the body that is related to a variety of immunological reactions. The effect of flaxseed supplementation on body weight and ody composition: a systematic review and meta-analysis of 45 randomized placebo-controlled trials. Epiandrosterone . Some people use black seed oil supplements to treat certain health conditions, including arthritis, allergies, asthma, and diabetes, and maintain a healthy weight. Taking flaxseed along with diabetes medications might cause blood sugar to drop too low. Flaxseed might make these estrogen-containing drugs less effective. Taking flaxseed by mouth may help reduce. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. A phase III, randomized, placebo-controlled, double-blind trial of flaxseed for the treatment of hot flashes: North Central Cancer Treatment Group N08C7. Medications are the primary treatment for hypertension; however, adherence to drug regimens is low (~50 %). Flaxseed is often mixed with foods and used in baked goods, such as muffins, breads, and snack bars. View abstract. Flaxseed supplementation (not dietary fat restriction) reduces prostate cancer proliferation rates in men presurgery. There is a problem with According to WebMD, "Research suggests that plant omega-3s help the cardiovascular system through several different mechanisms, including anti-inflammatory action and normalizing the heartbeat. Nesbitt PD, Lam Y, Thompson LU. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Gholami Z, Akhlaghi M. The effect of flaxseed on physical and mental fatigue in children and adolescents with overweight/obesity: a randomised controlled trial. Khalatbari Soltani S, Jamaluddin R, Tabibi H, Mohd Yusof BN, Atabak S, Loh SP, Rahmani L. Effects of flaxseed consumption on systemic inflammation and serum lipid profile in hemodialysis patients with lipid abnormalities. National Center for Complementary and Integrative Health. View abstract. A prospective study of dietary fat and risk of prostate cancer. How fast does psyllium work? Similar to any other medication, Trulicity (dulaglutide) may interact with certain drugs or health conditions. Anaphylaxis caused by flaxseed. Flaxseed is a commonly recommended and used dietary supplement today. Thompson LU, Rickard SE, Cheung F, et al. Mayo Clinic does not endorse companies or products. View abstract. Lampe JW, Martini MC, Kurzer MS, et al. Can Apoaequorin Really Improve Your Memory? Some vitamins and supplements can interfere with blood-thinning blood pressure drugs, Dr. Glatter says. View abstract. Here are 9 teas that help treat stomach problems. View abstract. View abstract. Eur J Clin Nutr. Brooks JD, Ward WE, Lewis JE, et al. It is created by eHealthMe based on reports of 563 people who take Flaxseed and . Vomiting and nausea may also be signs of an allergy. View abstract. 2005-2023 Healthline Media a Red Ventures Company. Jenkins DJ, Kendall CW, Vidgen E, et al. Possible side effects include: Diarrhea and loose stools Worsening constipation 1 These side effects can be minimized by taking flaxseed oil with plenty of water and by taking it at recommended doses. It is also used for many other conditions, but there is no good. A September 2014 article published in the Journal of Food Science and Technology says flaxseed oil is the best plant source of the essential fat. Available for Android and iOS devices. Am J Epidemiol 2007;165:514-23. View abstract. February 23, 2023. are using cholesterol-lowering drugs. Follow all directions on the product label and package. We avoid using tertiary references. OTHER NAME(S): Alasi, Aliviraaii, Brown Flaxseed, Brown-Seeded Fl, Flax (Linum usitatissimum) is a food and fiber crop. J Clin Oncol 2007;25:648-55. View abstract. Int J Cancer 2006;119:925-31. There is some concern that it might interfere with the body's ability to absorb medications taken by mouth because it might sweep them out of the digestive tract too quickly. However, a high intake of. The inhibitory effect of flaxseed on the growth and metastasis of estrogen receptor negative human breast cancer xenografts is attributed to both its lignan and oil components. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Flaxseed oil might lower blood pressure. Consumption of a flaxseed-rich food is not more effective than a placebo in alleviating the climacteric symptoms of postmenopausal women. Drug class: Herbal products. Nutr Res. List Flaxseed side effects by likelihood and severity. Am J Clin Nutr 2009;90:288-97. Moderate to vigorous physical activity, particularly aerobic exercise, has been shown to be associated with lower risk of bone fractures in women being treated with aromatase inhibitors. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Yari Z, Rahimlou M, Eslamparast T, Ebrahimi-Daryani N, Poustchi H, Hekmatdoost A. Flaxseed supplementation in non-alcoholic fatty liver disease: a pilot randomized, open labeled, controlled study. Ultimately, if flaxseed is to blame, an upped dosage of levothyroxine medication is probably needed going further. Wang C, Makela T, Hase T, et al. View abstract. View abstract. Flax seed oil is used to treat the following conditions: Atopic Dermatitis; Constipation; Eczema; High Cholesterol; Peripheral Neuropathy; Prostate Cancer; green tea. View abstract. Estrogens. A randomized controlled trial of the effect of dietary soy and flaxseed muffins on quality of life and hot flashes during menopause. 2014 Jul;64(1):53-9. Hypertension. View abstract. Research suggests that hemp oil has health benefits. Dietary fat and prostate cancer: current status. Read More Created for people with ongoing healthcare needs but benefits everyone. Can J Physiol Pharmacol. J Nutr 2010;140:1937-42. Flaxseed oil is available in liquid and capsule form. 2019;29:41-48. Mani UV, Mani I, Biswas M, Kumar SN. Plasma phytoestrogens and subsequent breast cancer risk. Finnegan YE, Minihane AM, Leigh-Firbank EC, et al. A deficiency of vitamin B12 can cause permanent neurological and nerve damage as well as mood changes and decreased energy. However, it may cause undesirable side effects if you have a preexisting medical condition, use certain medications, or take the wrong dosage. Examples of barbiturates and medications that have barbiturate actions include: Felbatol (felbamate) Nutritional attributes of traditional flaxseed in healthy young adults. Potent antihypertensive action of dietary flaxseed in hypertensive patients. Excess sodium disturbs the water. View abstract. Sairanen U, Piirainen L, Nevala R, Korpela R. Yoghurt containing galacto-oligosaccharides, prunes and linseed reduces the severity of mild constipation in elderly subjects. Does Flaxseed Interfere With Cholesterol Medication? Sun J, Bai H, Ma J, et al. View abstract. Most of the animal studies have focused on breast cancer. Other uses not proven with research have included enlarged prostate, heart disease, constipation, high blood pressure, irritable bowel syndrome, menopausal symptoms, weight loss, diverticulitis, attention deficit-hyperactivity disorder (ADHD), cancer (prostate, breast, lung, endometrial), and others. Skip the missed dose if it is almost time for your next scheduled dose. Similar to the hormone estrogen, phytoestrogens might have anti-cancer properties. Rhee Y, Brunt A. Flaxseed supplementation improved insulin resistance in obese glucose intolerant people: a randomized crossover design. Javidi A, Mozaffari-Khosravi H, Nadjarzadeh A, Dehghani A, Eftekhari MH. However, research has shown that flax may not be effective in treating this condition. Am J Clin Nutr 1995;61:62-8. Asia Pac J Clin Nutr. Whether you are treated by a medical doctor or a practitioner trained in the use of natural medicines/supplements, make sure all your healthcare providers know about all of your medical conditions and treatments. The effect of flaxseed and wheat bran consumption on urinary estrogen metabolites in premenopausal women. View abstract. Excretion of the lignans enterolactone and enterodiol and of equol in omnivorous and vegetarian postmenopausal women and in women with breast cancer. Urology 2001;58:47-52. WebMD does not provide medical advice, diagnosis or treatment. Cats require certain vitamins, minerals, and . Flax and flaxseed oil: An ancient medicine and modern functional food. Appetite 2012;58:490-5. Int J Cancer 2005;116:793-8. Eur J Clin Nutr. It's most often used for constipation (a common hypothyroid symptom) and touted for many other supposed health benefits. You may also want to be careful combining flaxseed oil and warfarin, which is a blood-thinning medication that prevents the formation of blood clots. Polypodium Leucotomos - Inotersen. Common interactions include back pain among females and flushing among males. These might be signs of anaphylactic shock. (n.d.). The effects of dietary flaxseed on cardiac arrhythmias and claudication in patients with peripheral arterial disease (1). Mirghafourvand M, Mohammad-Alizadeh-Charandabi S, Ahmadpour P, Javadzadeh Y. Flaxseed may interfere with the absorption of some medications. Touillaud MS, Thiebaut AC, Fournier A, et al. View abstract. Here are the 15 best vitamin brands to help. Additionally, you may have to avoid the supplement completely. View abstract. J Investig Allergol Clin Immunol. Research investigating the health benefits of flaxseed oil, however, show some promise for the plant oil. Limited animal studies have found that flaxseed and flaxseed oil do not interfere with actions of tamoxifen or trastuzumab (medications used for breast cancer treatment) and may even enhance their effectiveness. the unsubscribe link in the e-mail. The evidence is mixed as to whether flaxseed or flaxseed oil has any effect on the prostate or the risk of prostate cancer. Oncology Nutrition advises that you should discuss the use of flax seeds with your doctor and avoid the use of flaxseed oil altogether because it provides no benefit to those with prostate cancer. Hypertension. While over-the-counter drugs can help relieve constipation, natural remedies like flaxseed have proven to be effective in some people. Flaxseeds are high in potassium. Consuming flaxseed oil may lower your blood pressure. View abstract. Flaxseed interacts with 583 drugs . View abstract. Demark-Wahnefried W, Robertson CN, Walther PJ, et al. Select a condition to view a list of vitamins. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023 . Red raspberry leaves have been used during pregnancy and to treat various ailments for centuries. Phytother Res 2021;35(7):3781-3791. 2015;145:758. Many people take fish oil supplements daily, but you may not know whats the right dosage for you. To help you remember, take it at the same time(s) each day. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Am J Clin Nutr 1999;69:549-55. View abstract. Adlercreutz H, Heikkinen R, Woods M, et al. Effects of linseeds on the symptoms of irritable bowel syndrome: a pilot randomised controlled trial. Common interactions include arthralgia among females and diarrhoea among males. Hashempur MH, Homayouni K, Ashraf A, Salehi A, Taghizadeh M, Heydari M. Effect of Linum usitatissimum L. (linseed) oil on mild and moderate carpal tunnel syndrome: a randomized, double-blind, placebo-controlled clinical trial. Flaxseed is an herbal supplement used to treat constipation (chronic), enlarged prostate (oil), cancer (prevention), diabetes, diverticulitis, inflammation of the small intestine and/or the stomach, high cholesterol, irritable bowel syndrome, menopausal symptoms, myocardial infarction prevention (oil), skin inflammation, and systemic lupus Azrad M, Vollmer RT, Madden J, Dewhirst M, Polascik TJ, Snyder DC, Ruffin MT, Moul JW, Brenner DE, Demark-Wahnefried W. Flaxseed-derived enterolactone is inversely associated with tumor cell proliferation in men with localized prostate cancer. Natural Medicines. You may report side effects to FDA at 1-800-FDA-1088. View abstract. Kidney Int 1995;48:475-80. J Natl Cancer Inst 1999;91:414-28. https://nccih.nih.gov/health/flaxseed/ataglance.htm. Flaxseed supplementation in hyperlipidemic patients. Rickard SE, Yuan YV, Thompson LU. Khalesi S, et al. Comparisons of the effects of different flaxseed products consumption on lipid profiles, inflammatory cytokines and anthropometric indices in patients with dyslipidemia related diseases: systematic review and a dose-response meta-analysis of randomized controlled trials. Low vitamin D levels have been associated with a higher likelihood of thyroid disease. Urinary lignan and isoflavonoid excretion in premenopausal women consuming flaxseed powder. Speak with a healthcare provider to find out what type of product and dose might be best for a specific condition. The beneficial potential of flaxseed to reduce blood pressure (especially diastolic blood pressure) may be greater when it is consumed as a whole seed and for a duration of >12 wk. Medically reviewed by Drugs.com on Jul 25, 2022. View abstract. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. The most common medication used in women with PCOS is the insulin-sensitizer metformin. Flaxseed is used for constipation, diabetes, high cholesterol, obesity, and swelling of the kidneys in people with lupus. Bloedon LT, Balikai S, Chittams J, et al. those that alter your blood flow and bleeding, including: some nonsteroidal anti-inflammatory drugs, like ibuprofen and naproxen. Cockerell KM, Watkins AS, Reeves LB, et al. Bloedon LT, Szapary PO. View abstract. Do not take this medication for more than 7 days unless directed by your doctor. 2021;60(1):287-298. If you take insulin or other medication for diabetes, consult your physician before consuming flaxseed meal. Even though it's just a food, flaxseed oil may not mix well with certain health conditions or medications. Appl Physiol Nutr Metab 2009;34:89-98. Flaxseed can act like a laxative. Dietary flaxseed enhances the inhibitory effect of tamoxifen on the growth of estrogen-dependent human breast cancer (mcf-7) in nude mice. It may take 1 to 3 days before this medication starts working. Our website services, content, and products are for informational purposes only. If you have a condition or take a medication that lowers your blood pressure, adding this supplement to your diet could cause complications. Drink plenty of water each day while you are taking this product. View abstract. 2016 Jun;35(3):615-25. Flax seeds are considered to help with constipation. Plasma enterolignan concentrations and colorectal cancer risk in a nested case-control study. Flax is the seed of a plant called Linum usitatissimum, and is also known as Flax Seed, Alasi, Aliviraaii, Brown Flaxseed, Brown-Seeded Flax, Echter Lein, Flachssamen, Flax Hull, Flax Lignans, Gemeiner Flachs, Graine de Lin, Kattan, Keten, Leinsamen, Lignans, Lin, Olagineux, Lin Textile, Linaza, Lini Semen, Linho, Lino, Linseed, Lint Bells, Allman, M. A., Pena, M. M., and Pang, D. Supplementation with flaxseed oil versus sunflowerseed oil in healthy young men consuming a low fat diet: effects on platelet composition and function. Alonso L, Marcos ML, Blanco JG, et al. Mousavi Y, Adlercreutz H. Enterolactone and estradiol inhibit each other's proliferative effect on MCF-7 breast cancer cells in culture. There is a chance you may have an allergy to flax seeds and flaxseed oil. Dietary phytoestrogens are not associated with risk of overall breast cancer but diets rich in coumestrol are inversely associated with risk of estrogen receptor and progesterone receptor negative breast tumors in Swedish women. Nutr Cancer 1997;27:26-30. Cabbage - Sulconazole. Dietary phytoestrogen intake--lignans and isoflavones--and breast cancer risk (Canada). View abstract. Alpha-linolenic acid in the treatment of rheumatoid arthritis. https://naturalmedicines.therapeuticresearch.com. Anticoagulant and anti-platelet drugs, herbs and supplements. The Mayo Clinic warns that using flaxseed oil with this blood thinner, or any other anticoagulant, may increase your risk of bleeding. You should use these products with caution. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. Effects of dietary flaxseed in women with cyclical mastalgia. View abstract. Would you believe hundred grams of flaxseeds contain 813 mg of potassium. Int J Cancer 2006;119:2376-81. 016 Sep 1;21:70. J Clin Endocrinol Metab 2002;87:1527-32.. View abstract. Barre DE, et al. Flaxseed. There is a high chance you may have an allergy to flaxseeds and flaxseeds oil. Do not take flax without medical advice if you are using any of the following medications: any medications for diabetes or high blood pressure; This list is not complete. Fact Checked by Paul Bossung. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination. Research is strongly showing that long-term use of metformin and at high doses (1.5mg or higher daily) can deplete levels of vitamin B12. Lignans and flavonoids inhibit aromatase enzyme in human preadipocytes. Why Doesn't the U.S. Have at-Home Tests for the Flu? Oral drugs. other information we have about you. Yari Z, Rahimlou M, Poustchi H, Hekmatdoost A. Flaxseed supplementation improves anthropometric measurements, metabolic, and inflammatory biomarkers in overweight and obese adults. When taken in the right doses and in the short term, flaxseed oil is usually safe for most adults. The omega-3 fatty acids in flaxseed meal by interact negatively with blood-thinning medications. Reprod Toxicol 2007;23:397-406. These medications may interact and cause very harmful effects. View abstract. But it can interfere with the absorption of some medications and supplements.Take oral agents one hour before -- or two hours after -- flaxseed to prevent decreased absorption. Though your body can make many types of fat on its own, such as cholesterol, omega-3 fatty acids are essential and must be supplied from outside sources. This content does not have an Arabic version. Dietary alpha-linolenic acid is associated with reduced risk of fatal coronary heart disease, but increased prostate cancer risk: a meta-analysis. 2019;10:218. Flaxseed oil contains ALA, which your body primarily uses as a source of energy, according to Harvard T.H. Does Flaxseed Interact with other Medications? De Stefani E, Deneo-Pellegrini H, Boffetta P, et al. View abstract. Haidari F, Banaei-Jahromi N, Zakerkish M, Ahmadi K. The effects of flaxseed supplementation on metabolic status in women with polycystic ovary syndrome: a randomized open-labeled controlled clinical trial. JAMA Pediatr. Advertising revenue supports our not-for-profit mission. Answer: Atorvastatin (Lipitor), rosuvastatin (Crestor), and other cholesterol-lowering statin drugs can be affected by taking supplements and can affect your ability to absorb certain vitamins and minerals. CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. View abstract. Chan School of Public Health: "Omega-3 Fatty Acids: An Essential Contribution", National Institutes of Health National Center for Complementary and Integrative Health: "Flaxseed and Flaxseed Oil", Harvard Health Publishing: "Why Not Flaxseed Oil? Flaxseed in pediatric hyperlipidemia: a placebo-controlled, blinded, randomized clinical trial of dietary flaxseed supplementation for children and adolescents with hypercholesterolemia. (2014). Tell each of your health care providers about all medicines you use now and any medicine you start or stop using. Flaxseed can be used whole or crushed, or in a powder form as meal or flour. Mammalian lignans inhibit the growth of estrogen-independent human colon tumor cells. Rose DP. What Are the Benefits of Flaxseed Oil Pills? Debra Rose Wilson, PhD, MSN, RN, IBCLC, AHN-BC, CHT. View abstract. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. Flaxseed oil contains a-linolenic acid (ALA), which the body can break down into an omega-3 fatty acid. We'll take a look at just what makes hemp oil beneficial and which conditions may improve from. Nutr J 2011;10:44. Thanos J, Cotterchio M, Boucher BA, et al. Let's Find Out View abstract. However, you should always talk to your primary care provider to discuss flaxseed oil dosage and safety before adding the plant oil to your daily routine. There are 10 disease interactions with Cymbalta (duloxetine) which include: Liver Disease Renal Disease Depression Diabetes Glaucoma Hypertension Hyponatremia Mania Seizures Urinary Tract Obstruction Is it safe to eat raw flaxseed during pregnancy? Mayo Clinic does not endorse any of the third party products and services advertised. View abstract. Flaxseed (Linum usitatissimum) and flaxseed oil, which comes from flaxseed, are rich sources of the essential fatty acid alpha-linolenic acid a heart-healthy omega-3 fatty acid. Am J Clin Nutr 1994;60:122-8. Aitken-Saavedra J, Chaves Tarquinio SB, De Oliveira da Rosa WL, et al. Mohammadi-Sartang M, Sohrabi Z, Barati-Bodaji R, Raeisi-Dehkordi H, Mazloom Z. Flaxseed supplementation on glucose control and insulin sensitivity: a systematic review and meta-analysis of 25 randomized, placebo-controlled trials. J Hum Nutr Diet 2012;25:435-43. J Am Coll Nutr 2001;20:398S-402S. View abstract. Haghighatsiar N, Askari G, Saraf-Bank S, Feizi A, Keshmiri H. Effect of flaxseed powder on cardiovascular risk factor in dyslipidemic and hypertensive patients. 2014;22:43. Flaxseed: a potential treatment for lupus nephritis. Am J Clin Nutr 1999;69:395-402. Though your body contains enzymes that convert ALA from flaxseed oil into EPA and DHA, your body only converts 10 to 15 percent of the ALA, says Harvard Health Publishing. You can learn more about how we ensure our content is accurate and current by reading our. View abstract. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). Menopause 2006;13:631-42. Yari Z, Cheraghpour M, Hekmatdoost A. Flaxseed and/or hesperidin supplementation in metabolic syndrome: an open-labeled randomized controlled trial. Flaxseed has most often been used by adults in doses of 20-30 grams by mouth daily. It's possible that taking flaxseed oil might increase the risk of bleeding. This might alter the effects of flaxseed. Flaxseed and its lignan and oil components reduce mammary tumor growth at a late stage of carcinogenesis. DOI: Possible interactions with: Flaxseed oil. View abstract. 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